AI Drug Discovery for Solid-Tumor Oncology

Rank solid-tumor targets by their full evidence record. Before bench resources commit.

Avenzo pulls structured evidence from millions of papers and trial registries, scores each candidate target against the literature, and delivers a ranked assessment your discovery team can act on.

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The Problem

The target selection problem costs discovery teams months

Oncology research programs screen dozens of candidate targets each cycle. The evidence that separates a high-confidence target from a dead end is scattered across tens of thousands of papers, preprint archives, and trial registries. Synthesizing it manually takes weeks. Avenzo compresses that to hours.

Oncology drug discovery attrition: over 90 percent of candidates that enter clinical development fail, often because target evidence was incomplete at selection.

How It Works

From query to ranked evidence in one workflow

01

Define the query

Specify the tumor type, pathway context, and therapeutic hypothesis. Avenzo scopes the evidence search accordingly.

02

Evidence ingestion and scoring

The platform ingests preclinical literature, clinical context data, and computational predictions. Each target gets a multi-dimensional evidence score.

03

Ranked report delivery

Targets are ranked by composite evidence depth. Your team receives a structured report with score breakdowns, source counts, and confidence flags.

Use Cases

Where discovery teams use Avenzo

Early target screening

Triage a long list of genomic alterations down to the candidates with the strongest literature support before committing any assay resources.

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Go/no-go evidence review

Before advancing a target from computational nomination to assay development, validate the evidence depth across independent source types.

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Portfolio triage

Across a broader oncology pipeline, rank multiple active targets by comparative evidence quality to focus resource allocation.

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Evidence depth that moves faster than manual review

40M+

papers and trial records in the evidence corpus

based on our indexed literature database as of early-access beta

6hr

median time from query to ranked report

across early-access pilot runs

12x

more evidence sources per target than manual literature review captures in a typical week-long synthesis

internal benchmark across early-access pilots, 8 research queries

2024

founded in San Diego by oncologists and computational biologists

Early Access

What early-access participants found

We used to spend three weeks synthesizing target evidence before each portfolio review. Avenzo compressed that to an afternoon. The ranked output maps directly onto our go/no-go criteria.

Dr. Lena Farooq Senior Scientist, Target Identification, at a large oncology drug discovery organization early-access program participant

The multi-source scoring is what made it credible for us. We did not want a black box. Seeing the preclinical versus clinical context evidence broken out by source type gave us something we could defend in a target review meeting.

Dr. James Okafor Head of Computational Biology, at an independent oncology research center pilot design partner

Built by people who have lived the problem

Athena Countouriotis, CEO and Co-Founder

Athena Countouriotis

CEO & Co-Founder

Oncology clinical development and translational research background. Years building programs that bridge computational target identification and experimental validation in solid tumors.

Ravi Nair, CTO and Co-Founder

Ravi Nair

CTO & Co-Founder

Spent years building large-scale biomedical text mining and evidence integration systems. Background in natural language processing applied to scientific literature.

Naomi Stein, CSO and Co-Founder

Naomi Stein

CSO & Co-Founder

Background in solid tumor biology and computational target validation. Worked on translational oncology programs where target evidence quality directly determined resource commitment decisions.

Early Access

Join the early-access program

Avenzo is accepting a limited cohort of oncology research teams. Request access and a member of the team will be in touch.