Research and Perspectives

The Avenzo Blog

Methodology, evidence analysis, and perspectives on solid-tumor target identification from the Avenzo research team.

Latest Article

Evidence ranking for solid tumor target selection
Target Selection

Evidence Ranking in Solid-Tumor Target Selection: Why the Ordering Matters

Ranking targets by evidence quality rather than evidence volume changes which candidates reach the bench first. We examine the structural reasons the ordering matters and how a tiered evidence framework reshapes initial prioritization decisions.

9 min read
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All Articles

The data problem in oncology target selection
Methodology

The Data Problem in Oncology Target Selection: A Structural Analysis

7 min read
Early access to the target ranking engine
Product

Opening Early Access to the Target Ranking Engine

5 min read
Evidence quality tiers in drug discovery
Science

Evidence Quality Tiers: A Framework for Drug Discovery Target Validation

8 min read
From genomic alteration to druggable target
Target Biology

From Genomic Alteration to Druggable Target: Closing the Evidence Gap

7 min read
Solid tumor heterogeneity and target identification
Solid Tumors

Solid-Tumor Heterogeneity and the Target Identification Challenge

9 min read
The translational gap in oncology targets
Translational Research

The Translational Gap: Why Oncology Targets Fail After Promising Preclinical Data

8 min read
Pathway context in target ranking
Methodology

Pathway Context in Target Ranking: Beyond Single-Gene Evidence

6 min read
Literature mining for target evidence at scale
Technology

Literature Mining at Scale: How Avenzo Processes Target Evidence Across Thousands of Papers

7 min read
The cost of pursuing the wrong target
Economics

The Cost of the Wrong Target: Bench-Time Economics in Oncology Discovery

6 min read
Computational target prioritization for oncology teams
Technology

Computational Target Prioritization: A Practical Guide for Oncology Discovery Teams

8 min read
Multi-source evidence integration for target identification
Methodology

Multi-Source Evidence Integration: The Foundation of Reliable Target Identification

7 min read
Company

The Data Problem in Oncology: Why We Started Avenzo

The specific evidence synthesis problem in oncology target selection that led us to build Avenzo, and why we believe a structured approach to evidence quality changes which targets reach the bench.

8 min read