The Platform
A target ranking engine built on evidence, not intuition
Avenzo integrates preclinical literature, clinical context data, and computational predictions to score each solid-tumor target against the full available evidence record.
Evidence Corpus
What goes into the evidence corpus
Every analysis draws from four independent evidence streams, indexed and updated continuously.
Published research on target biology, cell-line evidence, and model organism data across oncology journals and preprint archives.
Trial registry data, outcome context from completed studies, and published clinical findings indexed by target and tumor type.
Pathway network models, protein interaction data, and computational target validation signals integrated as a third evidence dimension.
Somatic alteration frequency across tumor types, expression data context, and co-occurrence patterns that inform target prioritization.
Scoring Methodology
How evidence becomes a score
Each target is scored across three orthogonal evidence dimensions: preclinical support depth, clinical context alignment, and computational signal convergence. Dimension scores are weighted by evidence quality tier and integrated into a composite ranking. The output is a ranked list with per-dimension breakdowns so your team can inspect the reasoning.
Literature
Context
Signal
Example Output
The evidence report your team receives
Every analysis run delivers a structured target evidence report. Below is an illustrative output from an early-access analysis.
Workflow Integration
Fits into your existing discovery workflow
Avenzo is designed to complement, not replace, your internal research review. Query inputs match the format of a standard target review brief. Output reports are structured for direct use in portfolio review meetings and target advancement decisions.
Specify the tumor type, pathway context, and target list. Avenzo scopes the evidence search accordingly.
The platform ingests preclinical, clinical, and computational evidence. Each target receives a multi-dimensional evidence score.
Targets are ranked by composite evidence depth. Your team receives a structured report with score breakdowns and confidence flags.
Early Access
Request access to see a live analysis run
Avenzo is accepting a limited cohort of oncology research teams for early access. A member of the team will walk you through a live analysis run.