Use Cases
Where evidence-ranked targeting makes the biggest difference
Avenzo serves oncology discovery teams at the moments when a decision about which target to advance carries the highest long-term consequence.
Use Case 1
Initial target prioritization at program start
When a discovery team begins a new solid-tumor program, the starting target list often contains 8 to 30 candidates with varying evidence depth. Evaluating each one manually across preclinical, clinical context, and computational sources takes weeks and introduces individual analyst bias.
Avenzo delivers a structured, tier-weighted ranking of the full candidate list within a single analysis run. Teams use the ranked output to allocate experimental capacity to the top-ranked targets first, without spending weeks building the evidence case manually.
8 to 30 candidates
Use Case 2
Portfolio advancement decisions
Portfolio review meetings require teams to defend target advancement decisions with more than internal conviction. Reviewers ask whether the evidence base is sufficiently deep to justify the resource commitment.
Avenzo provides an externally consistent evidence summary that teams can present alongside their internal analysis. The per-dimension breakdown shows where evidence is strong and where gaps exist, supporting a more structured conversation about advancement risk.
Per-dimension evidence breakdown with confidence tier
Use Case 3
Identifying evidence gaps before committing bench time
A target that scores high on preclinical literature but low on clinical context alignment represents a specific risk profile: the mechanistic hypothesis is supported, but the translational evidence is thin. Recognizing this before committing to an expensive model system changes how the team designs the next experiment.
Avenzo's per-dimension breakdowns make evidence gaps explicit. Teams use this to design targeted gap-filling experiments, rather than discovering the gap after months of bench work in the wrong direction.
Experiments designed to fill identified evidence gaps, not repeat supported territory
Apply to Your Program
Run your current target list through the Avenzo engine
Early-access teams receive a full analysis run on their target list with a structured evidence report and a one-hour debrief session with the Avenzo team.